Fenbendazole is a broad spectrum benzimidazole anthelmintic used for the removal of various gastrointestinal parasites. It is effective against large strongyles (Strongylus edentatus, Strongylus equinus, Strongylus vulgaris), roundworms (including hookworms and whipworms) and the tapeworm genus Taenia, although it is not active against the Common Tapeworm Dipylidium caninum). It is also effective against Giardia, an intestinal protozoan which causes diarrhea. In addition, it is an effective treatment against lungworms and flukes. This medication is available as a blue and white elongated capsule made specifically for your pet at the request of your veterinarian.
It is important to note that fenbendazole is not an FDA approved drug and is therefore not marketed for use in humans. However, it is of increasing interest to researchers who are exploring its potential anticancer properties. In one recent study, Kyung-Sun Kang and Da-Hyun Kim found that fenbendazole induces cell cycle arrest in colorectal cancer cells and patient-derived colon cancer organoids.
In this study, mice with established EMT6 tumors were randomly assigned to groups treated with either fenbendazole or control drugs. When the tumor reached a volume of 1000 mm3, mice were euthanized and necropsied. The tumor growth rate was measured by determining the time it took for the tumor to grow from its initial volume to four times that volume. Neither unirradiated nor irradiated mice showed any differences in tumor growth rates after receiving fenbendazole. fenbendazole capsules
